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labmaster lucia mxa  (Labmaster)
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Bland-Altman and linear correlation plots for comparison of blood myxovirus resistance protein A (MxA) levels measured by point-of-care (POC) and reference methods in 228 febrile children. A , Bland-Altman plot presenting level of agreement between the <t>POC</t> <t>Labmaster</t> <t>LUCIA</t> MxA measurement and the reference enzyme immunoassay (EIA) analysis. The mean difference (−76 µg/L) between the methods is represented as a solid line and the 95% limits of agreement (from −409 to 257 µg/L) as dashed lines. B , Scatterplot showing linear correlation between the POC Labmaster LUCIA MxA measurement and the reference EIA analysis. Of 228 samples of febrile children, 188 were collected and analyzed by the attending pediatric emergency department personnel, and 40 were collected at the pediatric ward for infectious diseases and analyzed by the laboratory personnel. Abbreviations: EIA, enzyme immunoassay; MxA, myxovirus resistance protein A; SD, standard deviation.
Labmaster Lucia Mxa, supplied by Labmaster, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Bland-Altman and linear correlation plots for comparison of blood myxovirus resistance protein A (MxA) levels measured by point-of-care (POC) and reference methods in 228 febrile children. A , Bland-Altman plot presenting level of agreement between the POC Labmaster LUCIA MxA measurement and the reference enzyme immunoassay (EIA) analysis. The mean difference (−76 µg/L) between the methods is represented as a solid line and the 95% limits of agreement (from −409 to 257 µg/L) as dashed lines. B , Scatterplot showing linear correlation between the POC Labmaster LUCIA MxA measurement and the reference EIA analysis. Of 228 samples of febrile children, 188 were collected and analyzed by the attending pediatric emergency department personnel, and 40 were collected at the pediatric ward for infectious diseases and analyzed by the laboratory personnel. Abbreviations: EIA, enzyme immunoassay; MxA, myxovirus resistance protein A; SD, standard deviation.

Journal: The Journal of Infectious Diseases

Article Title: Evaluation of a Novel Point-of-Care Blood Myxovirus Resistance Protein A Measurement for the Detection of Viral Infection at the Pediatric Emergency Department

doi: 10.1093/infdis/jiae367

Figure Lengend Snippet: Bland-Altman and linear correlation plots for comparison of blood myxovirus resistance protein A (MxA) levels measured by point-of-care (POC) and reference methods in 228 febrile children. A , Bland-Altman plot presenting level of agreement between the POC Labmaster LUCIA MxA measurement and the reference enzyme immunoassay (EIA) analysis. The mean difference (−76 µg/L) between the methods is represented as a solid line and the 95% limits of agreement (from −409 to 257 µg/L) as dashed lines. B , Scatterplot showing linear correlation between the POC Labmaster LUCIA MxA measurement and the reference EIA analysis. Of 228 samples of febrile children, 188 were collected and analyzed by the attending pediatric emergency department personnel, and 40 were collected at the pediatric ward for infectious diseases and analyzed by the laboratory personnel. Abbreviations: EIA, enzyme immunoassay; MxA, myxovirus resistance protein A; SD, standard deviation.

Article Snippet: Since high specificity rather than high sensitivity is more important for a viral biomarker in minimizing the risk of undertreating a bacterial infection, a cutoff of 200 μg/L with a 100% diagnostic specificity and an excellent agreement between the Labmaster LUCIA MxA and reference test results seems applicable in clinical practice.

Techniques: Comparison, Enzyme-linked Immunosorbent Assay, Standard Deviation

Point-of-care Labmaster LUCIA myxovirus resistance protein A (MxA) levels in 188 febrile children at the emergency department, by etiology. For each group, the horizontal line represents the median, the box the upper and lower quartiles, and the whiskers the 95% confidence interval. For pairwise comparisons of groups “Viral infection” and “Viral-bacterial coinfection” with “Bacterial infection,” P < .001 for both comparisons by Mann-Whitney U test.

Journal: The Journal of Infectious Diseases

Article Title: Evaluation of a Novel Point-of-Care Blood Myxovirus Resistance Protein A Measurement for the Detection of Viral Infection at the Pediatric Emergency Department

doi: 10.1093/infdis/jiae367

Figure Lengend Snippet: Point-of-care Labmaster LUCIA myxovirus resistance protein A (MxA) levels in 188 febrile children at the emergency department, by etiology. For each group, the horizontal line represents the median, the box the upper and lower quartiles, and the whiskers the 95% confidence interval. For pairwise comparisons of groups “Viral infection” and “Viral-bacterial coinfection” with “Bacterial infection,” P < .001 for both comparisons by Mann-Whitney U test.

Article Snippet: Since high specificity rather than high sensitivity is more important for a viral biomarker in minimizing the risk of undertreating a bacterial infection, a cutoff of 200 μg/L with a 100% diagnostic specificity and an excellent agreement between the Labmaster LUCIA MxA and reference test results seems applicable in clinical practice.

Techniques: Infection, MANN-WHITNEY

Differentiation between viral and bacterial infections by point-of-care (POC) Labmaster LUCIA myxovirus resistance protein A (MxA) and MxA to C-reactive protein (CRP) ratio in febrile children at the emergency department (ED). Receiver operating characteristic (ROC) curves for differentiating between viral (n = 112) and bacterial (n = 34 for A and n = 33 for B ) infections in febrile children at the ED. A , ROC curve for POC MxA level. Area under the curve (AUC), 0.96 (95% confidence interval [CI], .94–.99). B , ROC curve for POC blood MxA (µg/L) to CRP (mg/L) ratio. AUC, 0.97 (95% CI, .95–.99).

Journal: The Journal of Infectious Diseases

Article Title: Evaluation of a Novel Point-of-Care Blood Myxovirus Resistance Protein A Measurement for the Detection of Viral Infection at the Pediatric Emergency Department

doi: 10.1093/infdis/jiae367

Figure Lengend Snippet: Differentiation between viral and bacterial infections by point-of-care (POC) Labmaster LUCIA myxovirus resistance protein A (MxA) and MxA to C-reactive protein (CRP) ratio in febrile children at the emergency department (ED). Receiver operating characteristic (ROC) curves for differentiating between viral (n = 112) and bacterial (n = 34 for A and n = 33 for B ) infections in febrile children at the ED. A , ROC curve for POC MxA level. Area under the curve (AUC), 0.96 (95% confidence interval [CI], .94–.99). B , ROC curve for POC blood MxA (µg/L) to CRP (mg/L) ratio. AUC, 0.97 (95% CI, .95–.99).

Article Snippet: Since high specificity rather than high sensitivity is more important for a viral biomarker in minimizing the risk of undertreating a bacterial infection, a cutoff of 200 μg/L with a 100% diagnostic specificity and an excellent agreement between the Labmaster LUCIA MxA and reference test results seems applicable in clinical practice.

Techniques: